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Age-Related Changes in Expression of CXCR4 and CCR5 on Peripheral Blood Leukocytes from Uninfected Infants Born to Human Immunodeficiency Virus Type 1-Infected Mothers

机译:出生于人类免疫缺陷病毒1型感染母亲的未感染婴儿外周血白细胞上CXCR4和CCR5表达的年龄相关变化

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摘要

Cross-sectional analysis of human immunodeficiency virus-exposed, uninfected infants revealed high proportions of CXCR4-expressing cells in their cord blood, which declined at 4.5 months and increased between 9 and 15 months to levels approaching those of uninfected adults. Proportions of CCR5-expressing cells, however, were very low in cord blood and subsequently increased with age.
机译:对未感染人类免疫缺陷病毒的婴儿进行的横断面分析显示,脐带血中表达CXCR4的细胞比例很高,在4.5个月时下降,在9到15个月内增加至接近未感染成年人的水平。然而,CCR5表达细胞的脐带血比例非常低,并且随年龄增长而增加。

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